Continuing upwards are three floors, a strange looking Joy Mutant prevents Brad from ascending the stairs to Floor 3. In order to get there, climb on top of the dresser in Floor 2, Room 2 and reach Floor 3 through a crack in the ceiling.
Firstly, the four hidden switches must be pressed. Walk to the tiles specified below and press the action button to activate them. They are located as follows:
|Floor 1, Room 4||Floor 2, Room 1||Floor 2, Room 4||Floor 3, Room 1|
Marty's head and neck stretching from the screen, and bile scattered everywhere. Marty's face is similar to that in LISA: THE FIRST, linking the abuse Lisa received to that of Brad. The bile everywhere may imply that Brad was also sexually abused by Marty as well. The music played in here is called "Don't Go In There", meaning 'don't go in that room' or a possible sexual double entendre. To the right is a hole in the wall that, once all hidden switches have been pressed, allows entrance.
Joy Mutant. The Joy Mutant is "Completely gone and is done killing". This could mean that once a Joy Mutant has fulfilled its deepest desire (this one killing a scientist), they become forever lost within their own mind. Beside the Mutant are three pieces of Joy. Here lies some of the best items in the game: a Dandy Boy, a Snubby and a Silk Poncho.
Dr. Yado's trumpet. Meaning that these mutants either worship Yado, or that the trumpet has a great hold on them.
- This entire area is a callback to the Bile Town from LISA the first, from the beige and red bile everywhere to the face warped mutants, it even plays the exact same song that plays in the town appropriately called "Bile".
Area 2 Crossroads • Roulette • Construction • Body Path • Muscle Cave • Bob's Dojo • Muddy Waters • The Beehive • Fishman Town • Skull Town • Nice Homes • Joy Lab • Wallys • Garbage Island • Resort Island • Dismal Island • Area 2/3 Transition